Hamilton Mill Pediatrics

Chapter 5: Conclusions, Implications and Recommendations for further

Conclusions and implications:

The role of histamine in mental illness has been theorized for decades, but the fields of conventional and alternative medicine have been slow to influence histamine against mental health. In addition, the vast majority of conventional and alternative practitioners do not realize that Vitamin C has powerful antihistamine effects, which may be beneficial to both physical and mental health. Conventional medicine uses pharmaceutical antihistamines to deal with complaints related to histamine physical, mental and sometimes those. As mentioned above, pharmaceutical antihistamines have several side effects, many of deteriorating mental health. It is lamentable that the vast majority of alternative practitioners are ignorant of the effects antihistamine vitamin C. It is the purpose of this thesis to provide vitamin C antihistamine effects, particularly in regard to the treatment of various forms of mental illness.

The proof of the positive impact of vitamin C on mental health is convincing. Vitamin C can act as a mild antidepressant via stimulating cAMP levels. Low levels of cAMP are associated with depression. Vitamin C also helps to produce norepinephrine, which, like cAMP, is often low in depression. In fact, the camp is down the path of norepinephrine, which is the way that many pharmaceutical use antidepressants to improve mood. Vitamin C also hydroxy dopamine to help train norepinephrine (Goodman et al., 1996).

Vitamin C, when used at high doses, can potentially reduce anxiety (Balch and Balch, 1997). As mentioned previously, the brain is constantly trying to maintain the level of vitamin C constant, regardless of the levels are low in the rest of the body. So, the question arises: how can low or high levels of vitamin C on mental health, assuming that a constant concentration in the brain? A plausible explanation is as follows: the total pool of vitamin C in the body can become more oxidized than reduced. Recall that only the oxidized vitamin C enters the brain, where it is then reduced. If there is not enough reducing agents in the brain, and vitamin C remain oxidized, and therefore most of its properties rendered useless. Reduction of vitamin C modulates levels of dopamine in the brain, and can therefore act as a natural antipsychotic in reducing the high rate of dopamine. It also helps secrete oxytocin, a hormone of pleasure, which improves mood. As mentioned above, ascorbate promotes myelin formation (Rice, 2000, p. 214). Vitamin C also inhibits the release of the stress hormone cortisol, which beyond for extended periods may precipitate depression. It also helps protect the brain against the neurotoxicity induced by drugs, probably by its antioxidant effects.

However, by far the largest positive effect on mental health that vitamin C is its effect antihistamine. Because, as mentioned previously, histamine has several adverse effects on mental health. Administration of histamine in the brains of animals reinforced the fear memory (Blandina et al., 2004). It is well known that histamine plays a major role in allergic reactions and allergic individuals are much more likely to suffer from depression (Firshein, 1996; Ossofsky, 1976). Histamine may directly cause depression behavior (Arrigo-Reina & Chiechio, 1998).

As mentioned previously, histamine, either directly or indirectly affects all the other important neurotransmitters, often by inhibiting the release of neurotransmitters (Brown, Stevens & Haas, 2001), thus theoretically cause anxiety, depression, or both. Anxiety can be caused by inhibition of histamine GABA, which slows nerve transmission. The d.